revolutionize chemical plants : A new study shows how an automated
system based on artificial intelligence can design, implement, test and
learn complex biochemical methods to produce lycopene, a red dye found
in tomatoes, which is commonly used as a food colorant. The study
opened the door for a wide range of biological applications.
in addition revolutionize chemical plants :The findings of the study, which combined artificial intelligence with a fully automated platform called the IllinoisBiological Foundry for Advanced Industrialization to access
bioprocessing, were published in the journal Nature Communications.
“Biological foundries are plants that mimic semiconductor foundries, but are designed for biological systems rather than electrical systems,” said Huimin Chao, a research leader and professor of chemical and molecular biology at the University of Illinois.
Because biology has many ways to produce chemicals:
the researchers believe that a system controlled by artificial intelligence,
which can choose from thousands of experimental iterations, is the
| system needed to reach real automation.
Previous efforts at biological foundries have yielded a wide range of chemical products, fuel, cells and proteins, but these studies have not been
fully automated, the researchers said.
“Previous studies in the development of biological foundries have focused primarily on only one element of design, construction, testing and learning, and the researcher should then intervene to conduct data analysis and plan for the next experiment,” Huimin Chao said. But our new system, called BioAutomata, finishes design, construction, testing and learning, leaving people out of the process. ”
The BioAutomata system has completed two rounds of complete
automated construction and improved lycopene production pathways,
including building lycopene pathways, converting DNA encoding paths
into host cells, cell growth, extracting and measuring lycopene
“The BioAutomata system:
it has reduced the likelihood of lycopene production pathways from more than 10,000 to about 100, as well as an improved amount of cells that increases lycopene production within weeks, reducing time and cost,” said Zhao.
finally Zhao believes that automated biological foundries will be a future
revolution in intelligent manufacturing, no less than what automation has brought to the automotive industry. “People made cars by hand 100 years ago, while the manufacturing process has become more efficient and effective thanks to automation, We imagine the same for the biological processing of chemicals and other substances
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